Finding de novo copy number variants in case-parent trios for oral clefts
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Detection of de novo copy number alterations in case-parent trios using the R package MinimumDistance
For the analysis of case-parent trio genotyping arrays, copy number variants (CNV) appearing in the offspring that differ from the parental copy numbers are often of interest (de novo CNV). This package defines a statistic, referred to as the minimum distance, for identifying de novo copy number alterations in the offspring. We smooth the minimum distance using the circular binary segmentation ...
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تاریخ انتشار 2012